Mental Health / Psychiatry
Peer-reviewed studies and reviews on Deep TMS for Depression.
Showing Depression · 55–72 of 95
The objective of this study was to evaluate the effectiveness of repetitive transcranial magnetic stimulation (rTMS) using an H1 coil as a treatment for hopelessness in individuals diagnosed with major depressive disorder (MDD). Methods: A randomized controlled trial was conducted in a…
There is a growing interest in accelerated dosing regimens for repetitive transcranial magnetic stimulation (rTMS), involving multiple daily sessions. This Phase IV study assessed the safety, efficacy, and lasting effects of various accelerated protocols of Deep Transcranial Magnetic Stimulation (Deep TMS) applied…
Existing evidence suggests a concurrent improvement in depressive symptoms alongside obsessive-compulsive disorder (OCD) symptoms during cognitive behavioral therapy (CBT), even though depression is not the primary focus of the intervention. Studies exploring the temporal and mediational links between OCD and depressive symptoms…
Transcranial magnetic stimulation (TMS) is a non-invasive method widely proven to be effective in treating major depressive disorder (MDD) and is increasingly applied to various neuropsychiatric conditions. However, the conventional TMS has limitations, as it can only activate a small fraction of…
A history of adverse childhood experiences (ACEs) is known to be associated with poorer depression treatment outcomes. It is unknown how ACEs impact outcomes from Transcranial Magnetic Stimulation (TMS) treatment for depression. Objective: Assess whether a history of ACEs impact depression outcomes…
The safety and efficacy of the H1 Coil Deep TMS for MDD was shown in an international multicenter, randomized, controlled trial (RCT) with 212 subjects resulting in FDA clearance (Levkovitz et al., 2015), as well as in other RCTs (Filipcic et al., 2019; Matsuda et al., 2020). Deep TMS was…
Major depressive disorder (MDD) can benefit from novel interventions and personalization. Deep transcranial magnetic stimulation (Deep TMS) targeting the lateral prefrontal cortex (LPFC) using the H1 Coil, was FDA-cleared for treatment of MDD, however recent preliminary data indicate that targeting medial prefrontal…
Comorbid anxiety is common in patients with major depressive disorder (MDD), and these disorders may share a common underlying pathophysiology. Up to 85% of patients with depression experience significant anxiety symptoms, and comorbid depression occurs in up to 90% of subjects with…
OCD patients frequently have additional psychiatric illness, the most common being MDD. In 2018 the FDA cleared Deep TMS H7 Coil for the treatment of refractory OCD, based on the efficacy results of a multicenter study. The H7 Coil and its stimulation…
Repetitive transcranial magnetic stimulation (rTMS) is an evidence-based treatment option for major depressive disorder (MDD). However, comparisons of efficacy between the two FDA-approved protocols of rTMS modalities are lacking. Objective: The aim of this industry-independent, randomized-controlled, single-blind trial was to evaluate clinical outcome…
Repetitive deep transcranial magnetic stimulation (Deep TMS™) is efficacious for treatment resistant major depressive disorder (TRD) with the H1 coil by stimulating the prefrontal cortex, left more than right, at high frequency. Theoretically, the efficacy of Deep TMS could be optimized by…
Although repetitive transcranial magnetic stimulation (rTMS) with figure-of-8 (F8)-coil and deep transcranial stimulation (Deep TMS™)with H1-coil are promising treatments for unipolar major depressive disorder (MDD), the head-to-head comparisons in efficacy of both methods are lacking so far. Objective: The current study aims…
Deep TMS™ for treatment resistant depression uses high frequency pulses to stimulate the prefrontal cortex at an intensity of 120% of the resting motor threshold (120MT). Objective: Intensity and efficacy data from the active arm of the BrainsWaymulticenter clinical trial were analyzed…
The remission rate for patients with pharmacotherapy resistant depression who undergo standard deep repetitive transcranial stimulation (Deep TMS™) is almost 50%. This protocol consists of twenty daily treatment utilizing high frequency (18Hz, 1980 pulses) stimulation to the left prefrontal cortex(L-PFC). Objective: Deep…
Previous studies have shown safety and efficacy of deep repetitive transcranial magnetic stimulation (Deep TMS™) in treatment-resistant depression. However, little is known about predictors of response; i.e. it is difficult to predict which patients will benefit from the treatment. Objective: The aim…
High-frequency repeated transcranial magnetic stimulation (rTMS) as a treatment for major depressive disorder (MDD) has received FDA clearance for both the figure-of-8 coil (figure-8 coil) and the H1 coil. The FDA-clearedMDD protocols for both coils include high frequency (10–18 Hz) stimulation targeting…
The therapeutic options for treatment-resistant depression (TRD) encompass a range of neuromodulatorytechniques, including repetitive transcranial magnetic stimulation (rTMS). While rTMS is safe and has documented short-term efficacy, durability of antidepressant effects is poorly established. Objective: Assess existing evidence regarding durability of rTMS-induced…
Repetitive Transcranial Magnetic Stimulation (rTMS) is widely approved treatment for major depressive disorder (MDD). However, around 50% of individuals who recover from depression following rTMS interventions experience a relapse of depressive symptomatology by 12 months. The short-term durability of the rTMS treatment…
