Clinical Research
Peer-reviewed studies and reviews on Deep TMS for Basic Science Studies.
Showing Basic Science Studies · 1–18 of 26
A group of European experts reappraised the guidelines on the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) previously published in 2014 Methods: These updated recommendations take into account all rTMS publications, including data prior to 2014, as well as currently reviewed…
With respect to TMS coils used in TMS, the strength of a magnetic field decreases as it travels from its source at a rate of R-3 or 1/R3, where R is the distance from the center of the coil. For a typical figure-8…
In previous studies investigating cognitive processes using transcranial magnetic stimulation (TMS), researchers have explored responses to various stimulation parameters, such as frequency and coil location. This study aims to introduce an additional parameter by leveraging the spatial profiles of TMS coils to…
Transcranial magnetic stimulation (TMS) is a non-invasive method widely proven to be effective in treating major depressive disorder (MDD) and is increasingly applied to various neuropsychiatric conditions. However, the conventional TMS has limitations, as it can only activate a small fraction of…
This paper provides a concise overview of the adverse event profile of the H1, H4, and H7 Coils as studied in five (5) large, multicenter, randomized controlled trials (RCTs) consisting of 884 patients. The analysis is the most comprehensive review of both…
https://www.psychiatrist.com/jcp/depression/delivery-of-care/can-we-deliver-tms-patients-implanted-devices-practical-summary-recent-safety-recommendations/ This article addresses treatment guidance associated with performing TMS on patients with metallic implants, both medical and aesthetic. The theoretical concerns of conducting TMS with an implanted or non-removable device present are heating of the implanted device if it is made…
Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique that activates neurons via generation of brief pulses of high-intensity magnetic field. If these pulses are applied in a repetitive fashion (rTMS), persistent modulation of neural excitability can be achieved. The technique…
Electroconvulsive therapy (ECT) is a very effective treatment for major depression. This method involves robust nonfocal stimulation of the brain and can normalize both neurochemical alterations and depressive behavior in animal models. The authors hypothesized that short stimulation sessions of specific reward-related…
Approximately one third of all major depression patients fail to respond to conventional pharmacological antidepressants, and brain stimulation methods pose a promising alternative for this population. Recently, based on repeated multifactorial selective inbreeding of rats for depressive-like behaviors, we introduced a novel…
Long-term effects of repetitive transcranial magnetic stimulation (rTMS) have been associated with neuroplasticity, but most physiological studies have evaluated only the immediate effects of the stimulation on neurochemical markers. Furthermore, although it is known that baseline excitability state plays a major role…
Literature studies [Bersani et al., 2013] showed the ability to treat different neuropsychiatric disorders using the H1 coil. One of the coils belongs to the Hesed (H) coils, which have been developed specifically for the Deep Transcranial Magnetic Stimulation (Deep TMS™). Despite…
In the last few years, deep transcranial magnetic stimulation (Deep TMS™) has been used for the treatment of depressive disorders,which affect a broad range of age populations, from adolescents to aging people. To facilitate its clinical application, particular shapes of coils, including…
Modulating the function of the insular cortex could be a novel therapeutic strategy to treat addiction to a variety of drugs of abuse as this region has been implicated in mediating drug reward and addictive processes. The recent advent of the H-coil…
Stimulator technology has not changed significantly since the early days of TMS. Stimulation of a single-element coil using the sole channel of a TMS stimulator is standard. Objective: In this study, Roth et al. demonstrate the feasibility of a novel multi-channel stimulator…
The blood brain barrier is a highly selective anatomical and functional interface allowing a unique environment for neuro-glia networks. Blood–brain barrier dysfunction is common in most brain disorders and is associated with disease course and delayed complications. However, the mechanisms underlying blood–brain…
Publication & Date:Brain Stimulation 7:19 (2014) Investigators:A Ginou, Y Roth, A Zangen
Standard coils used in research and the clinic for noninvasive magnetic stimulation of the human brain are not capable of stimulating deep brain regions directly. As the fields induced by these coils decrease rapidly as a function of depth, only very high…
Noninvasive magnetic stimulation of the human central nervous system has been used in research and the clinic for several years. However, the coils used thus far stimulate mainly the cortical brain regions and could not stimulate deeper brain regions directly. Objective: The…
