Clinical Research
Peer-reviewed studies and reviews on Deep TMS for Mental Health / Psychiatry.
Showing Mental Health / Psychiatry · 1–18 of 208
Suicide is the 10th leading cause of death in US adults. Standard once-daily repetitive transcranial magnetic stimulation (rTMS) can reduce suicidal ideation. Yet, antidepressant and anti-suicidal effects often take several weeks to emerge, while rapid improvement is often required. Accelerated TMS has…
Cannabis use disorder (CUD) is a significant public health problem and no medical treatments have received regulatory approval to date. Deep repetitive transcranial magnetic stimulation (dTMS) provides brief powerful bursts of electromagnetic stimulation to brain networks implicated in psychiatric disorders and the…
rTMS can decrease cravings for drugs in a cue dependent fashion. dTMS is efficacious in smoking cessation with sustained quitting when combined with exposure therapy. However, no studies have utilized real world exposure to increase cravings prior to treatment with cocaine use…
Cocaine dependence is a substantial public health problem. Objective: The aim of this study is to evaluate the effect of high frequency deep transcranial magnetic stimulation (dTMS) on craving in patients with cocaine use disorder (CUD). Methods: Seven men with CUD and…
Late stages of Lyme disease include cognitive impairment, such as memory loss, slowed handling of information and substandard abstract reasoning. High frequency deep transcranial magnetic stimulation (dTMS) over the left prefrontal cortex (lPFC) has been shown to improve cognitive functioning for patients…
Anorexia nervosa (AN) is a complex disorder of unknown etiology, characterized by obsessions and compulsions around body shape, weight, and calorie intake. In the course of AN, 10%-30% will recover, while the rest will develop a treatment-resistant course with a high mortality…
Major Depressive Disorder (MDD) and Alzheimer's disease (AD) represent two of the most prevalent diseases worldwide. Notably, it is estimated that 30%-50% of individuals with AD have co-occurring MDD and there are overlapping symptoms across numerous domains. Methods: In this pilot study,…
The optimal dose (number of pulses per session) of repetitive transcranial magnetic stimulation (rTMS), using the H-coil, in major depressive disorder (MDD) has not previously been reported. Objective: To explore the relationship between rTMS dose and antidepressant effect, and collect data for…
Brainsway dTMS is FDA approved for TRD. Multiple studies prove the efficacy of Ketamine in TRD. There are case reports discussing the combination between Ketamine and rTMS in TRD Objective: To assess the clinical impact of Brainsway dTMS and Brainsway dTMS combined…
Major depressive disorder (MDD) is a leading cause of global disability and is notably prevalent in older adults. Deep transcranial magnetic stimulation (dTMS), specifically the H1-coil targeting the lateral prefrontal cortex, is approved for adults with treatment-resistant MDD and has shown promise…
Recruitment challenges are inherent in clinical research, and are particularly pronounced in older adults with depression, who often face unique barriers such as medical comorbidities and infrequent help-seeking behaviour. Neurostimulation techniques, like deep transcranial magnetic stimulation (dTMS), are often unfamiliar to patients…
Late-life depression (LLD) is a prevalent and often underdiagnosed condition in older adults, associated with significant cognitive, functional, and medical burdens. Conventional treatments frequently present limitations in this population, underscoring the need for safer, more effective alternatives. Objective: This review evaluates the…
Adaptive decision making requires the adjustment of behavior following an error in order to improve future performance, but OCD patients are characterized by abnormal error monitoring. For example, in cognitive tasks like Flanker or Stroop, reaction time (RT) following commission of an…
Transcranial magnetic stimulation (TMS) uses magnetic pulses to induce electrical current in the underlying neuronal tissue. A variety of TMS coils exist on the market, differing primarily in configuration, orientation, and flexibility of the wire windings of the coil. Deep TMSTM utilizes…
Tobacco smoking remains a leading preventable cause of morbidity and mortality worldwide. Deep transcranial magnetic stimulation (DTMS) using the H4 coil targets addiction-related circuits within the bilateral insula and prefrontal cortex and has demonstrated safety and efficacy in reducing smoking craving. However,…
Repetitive transcranial magnetic stimulation (rTMS) is an emerging treatment for several mental health conditions including substance use disorders. Symptom provocation before rTMS is hypothesized to activate disease-related neurocircuitry and enhance treatment effects. For addiction, craving induction is frequently used before treatment, but…
In 2020, Deep Transcranial Magnetic Stimulation (Deep TMS) gained FDA clearance for short-term smoking cessation, demonstrating efficacy comparable to pharmacotherapies with minimal side effects. Objective: This Phase IV registry study aimed to assess the real-world feasibility and efficacy of Deep TMS for…
Pathological gambling is classified in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, as an impulse- control disorder. Several studies showed positive preliminary results using TMS to treat addictions. Because TMS is a potential treatment for addictions, and because frontal cortex activity may be abnormal in pathological gamblers compared…
