Showing Clinical Research · 127–144 of 303
Benign essential blepharospasm (BEB) is a common form of focal dystonia. Besides pathology in the basal ganglia, accumulating evidence suggests pathologic changes in the anterior cingulate cortex (ACC). Objective: We conducted the present study to examine whether clinical and electrophysiologic effects of rTMS over the ACC…
The only serious side effect of transcranial magnetic stimulation (TMS) is the onset of a seizure during the stimulation. To avoid this adverse event, clinical trials have excluded patients on Clozapine, which lowers the seizure threshold. Several small reports demonstrate the safe use of 1 HZ repetitive…
The efficacy of deep transcranial magnetic stimulation (dTMS) for people with psychotic depression or schizoaffective disorder in the depressive phase is unknown. Objective: To determine the efficacy of dTMS with H1 coil in patients with schizophrenia and schizoaffective disorder depressive phase with or without psychosis. Methods: This is a retrospective chart…
The purpose of this review is to analyze all current literature related to different transcranial magnetic stimulation (TMS) modalities in the management of schizophrenia symptoms and compare the main controversies in the outcome measures. Methods: A comprehensive search in Ovid MEDLINE, APA…
Treatment-resistant schizophrenia (TRS) remains a therapeutic challenge. Deep transcranial magnetic stimulation (dTMS) is a novel technique targeting deep brain regions like the anterior cingulate cortex (ACC). Objective: This double-blind, randomized controlled trial investigated the efficacy and safety of low-frequency ACC-targeted dTMS in TRS. Methods: Twenty-three patients…
Deep transcranial magnetic stimulation (dTMS) has been proposed as a treatment method for patients with Attention Deficit/Hyperactivity Disorder (ADHD). Objective: To report on the treatment of two unmedicated patients with severe ADHD, combined type, using the dTMS H7 coil over the right prefrontal cortex. …
Studies of the pathophysiology of ADHD (Attention Deficit Hyperactive Disorder) have exemplified hemispheric asymmetry that possibly typifies ADHD patients from controls with right prefrontal under activation. Recent studies support possible effectiveness of rTMS (repetitive transcranial magnetic stimulation) as treatment for ADHD. Deciding about the target for stimulation is complex as there is…
Adolescent depression is a critical and growing public health concern, with high rates of treatment resistance and limited effective interventions. Deep Transcranial Magnetic Stimulation (Deep TMS) has been previously validated for adults, but data on its use in adolescents remain limited. Objective:To…
This systematic review aimed to evaluate and compare the safety and effectiveness of deep transcranial magnetic stimulation (dTMS) with high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) for individuals diagnosed with major depressive disorder (MDD). The study was motivated by the inconsistent findings of prior studies comparing dTMS and HF-rTMS for depression treatment. The…
Of late, the interest in accelerated treatment protocols in repetitive transcranial magnetic stimulation (TMS) for the treatment of depression and obsessive-compulsive disorder (OCD) has been gaining momentum. Studies have already found that the patterned theta burst stimulation is non-inferior to the standard…
Transcranial magnetic stimulation (TMS) is an intervention for treatment-resistant depression (TRD) that modulates neural activity. Deep TMS (dTMS) can target not only cortical but also deeper limbic structures implicated in depression. Although TMS has demonstrated safety in adolescents, dTMS has yet to…
Late-life depression (LLD) is a growing worldwide problem due to demographic changes, with limited treatment options due to high rates of pharmacotherapy adverse effects, accessibility of psychotherapy, and tolerability of electroconvulsive therapy. Novel neuromodulation techniques, such as repetitive transcranial magnetic stimulation (rTMS),…
Repetitive transcranial magnetic stimulation (rTMS) is an effective and well-established treatment for major depressive disorder (MDD). Deep TMS utilizes specially designed H-Coils to stimulate the deep and broad cerebral regions associated with the reward system. The improved depth penetration of Deep TMS…
Major Depressive Disorder (MDD) is a pervasive psychiatric condition effecting approximately 21 million adults in the U.S. (8.4%). An estimated 30–60% of patients are resistant to traditional treatment approaches (medications and talk-therapy), alluding to the need for additional options. Two promising treatment…
In the last couple of decades, newer treatment modalities, including neuromodulation through brain stimulation and psychosurgery have been examined to treat SRI-resistant OCD. A systematic review of brain stimulation treatments for resistant OCD suggested the efficacy of low-frequency TMS over the supplementary…
Anxiety disorders, including occupational stress and generalized anxiety disorder (GAD), are prevalent mental health conditions with significant impacts on individuals' daily functioning and quality of life. Deep Transcranial Magnetic Stimulation (TMS) is a non-invasive brain stimulation technique that holds promise in alleviating…
Evidence suggests that depressive symptoms tend to improve concurrently with obsessive-compulsive disorder (OCD) symptoms during cognitive behavioral therapy (CBT), despite depression not being the primary target of intervention. Studies examining the temporal or mediational relationships of OCD and depressive symptoms have indicated…
The background highlights the challenges faced by veterans with TRD, suicide risk, and PTSD symptoms, emphasizing the need for effective and durable treatment options. Objective: The primary objective is to assess the durability of deep transcranial magnetic stimulation in improving symptoms of…
