Showing Clinical Research · 145–162 of 303
It is normal for people to feel sad occasionally or have less enthusiasm for tasks that they once loved to do. However, when these feelings persist for an extended period, they may be a symptom of depression. Depression isn’t a defect of…
We conducted a direct comparison of the analgesic effects resulting from "superficial" and "deep" repetitive transcranial magnetic stimulation (rTMS) applied to the primary motor cortex in patients with central neuropathic pain. A total of fifty-nine consecutive patients were randomly assigned to receive…
Prior research has underscored the importance of cravings in substance use disorders (SUDs) and the potential of repetitive transcranial magnetic stimulation (rTMS) in mitigating these cravings. Crucial brain regions, including the medial prefrontal cortex (MPFC) and anterior cingulate cortex (ACC), are implicated…
Body Dysmorphic Disorder (BDD) involves an excessive preoccupation with a perceived physical flaw, leading to impaired functioning. There is currently no FDA-approved treatment for BDD, and many patients do not respond to standard therapies. Neuromodulation, particularly deep Transcranial Magnetic Stimulation (dTMS), emerges…
Deep transcranial magnetic stimulation (dTMS) represents an innovative non-invasive neuromodulation method built upon repetitive transcranial magnetic stimulation technology. The novel H-coil brings notable benefits to the treatment and mechanistic exploration of psychiatric and neurological disorders, attributed to its ability to stimulate deep…
Two patient cases illustrate the safety and potential clinical effectiveness of an accelerated deep transcranial magnetic stimulation (dTMS) protocol as an adjunctive approach in treating OCD. In contrast to the conventional once-daily protocol, the accelerated protocol may lead to quicker clinical improvement.…
In previous studies investigating cognitive processes using transcranial magnetic stimulation (TMS), researchers have explored responses to various stimulation parameters, such as frequency and coil location. This study aims to introduce an additional parameter by leveraging the spatial profiles of TMS coils to…
https://link.springer.com/article/10.1007/s12264-022-00919-5
We describe the first instance of dTMS application using H7 coil in an adolescent for childhood-onset OCD to evaluate the safety and efficacy of dTMS as an add-on treatment leading to the rapid and significant clinical improvement shown after 10 sessions in…
Transcranial magnetic stimulation (TMS) stands as a widely utilized noninvasive technique for brain stimulation in the context of psychiatric and cognitive disorders. In recent times, deep TMS (dTMS) has emerged as an advanced form of TMS capable of reaching deeper brain structures…
Obsessive-compulsive disorder (OCD) stands as one of the most prevalent neuropsychiatric disorders, surpassing the lifetime prevalence of schizophrenia and bipolar disorders. Many individuals with OCD do not adequately respond to currently available pharmacological and psychotherapeutic interventions. Consequently, there is growing interest in…
Current treatments for smoking cessation face limitations in terms of efficacy, particularly in achieving sustained abstinence. A substantial body of evidence points to the involvement of the insula in nicotine addiction. Objective: This study aimed to assess the effectiveness of bilateral repetitive…
Major depressive disorder (MDD) stands as one of the most prevalent and incapacitating health conditions globally, and regrettably, numerous patients do not exhibit positive responses to traditional antidepressant medication or talk therapy approaches. Deep transcranial magnetic stimulation (Deep TMS) has emerged as…
The objective of this study was to evaluate the effectiveness of repetitive transcranial magnetic stimulation (rTMS) using an H1 coil as a treatment for hopelessness in individuals diagnosed with major depressive disorder (MDD). Methods: A randomized controlled trial was conducted in a…
There is a growing interest in accelerated dosing regimens for repetitive transcranial magnetic stimulation (rTMS), involving multiple daily sessions. This Phase IV study assessed the safety, efficacy, and lasting effects of various accelerated protocols of Deep Transcranial Magnetic Stimulation (Deep TMS) applied…
Existing evidence suggests a concurrent improvement in depressive symptoms alongside obsessive-compulsive disorder (OCD) symptoms during cognitive behavioral therapy (CBT), even though depression is not the primary focus of the intervention. Studies exploring the temporal and mediational links between OCD and depressive symptoms…
Recently, the FDA granted clearance for deep repetitive transcranial magnetic stimulation (Deep TMS™) as a short-term smoking cessation treatment. However, there remains uncertainty regarding the characteristics of participants who are more likely to benefit from this treatment. Objective & Methods: This study…
Transcranial magnetic stimulation (TMS) is a non-invasive method widely proven to be effective in treating major depressive disorder (MDD) and is increasingly applied to various neuropsychiatric conditions. However, the conventional TMS has limitations, as it can only activate a small fraction of…
