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Mental Health / Psychiatry

Obsessive Compulsive Disorder (OCD)

Peer-reviewed studies and reviews on Deep TMS for Obsessive Compulsive Disorder (OCD).

Showing Obsessive Compulsive Disorder (OCD)  ·  19–36 of 41

  1. H7 Coil Deep Repetitive Transcranial Magnetic Stimulation in Patients With Obsessive-Compulsive Disorder: Do Factors Like Age, Sex, and Medication Affect Clinical Outcomes?

    Mudunuru AK, Jahnavi L, Reddy M, Reddy S, Valipay K, Balaji S, Chandresh N, Madhiha M, et al.

    Cureus

    Deep repetitive transcranial magnetic stimulation (DTMS), using the H7 coil, is an approved treatment for obsessive-compulsive disorder (OCD) by the United States Food and Drug Administration (US-FDA). The clinical efficacy and safety of accelerated regimens of DTMS have been previously studied extensively.…

    OCD
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  2. Efficacy of Adjunctive Deep Transcranial Magnetic Stimulation in Obsessive-Compulsive Disorder: A Randomized Sham-Controlled Study

    Reddy S, Goyal N, Shreekantiah U.

    J ECT

    Obsessive-compulsive disorder is one of the most common neuropsychiatric disorders with a higher lifetime prevalence than schizophrenia, often showing inadequate response to pharmacological and psychotherapeutic treatments. Objective: This study aimed to examine the efficacy of adjunctive deep transcranial magnetic stimulation (dTMS) in…

    OCD
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  3. EEG-based 3 Hz Intermittent Theta Burst Stimulation in a Middle-aged Female Resulted in Remission from Obsessive Compulsive Disorder

    Kammammettu, C; Mudunuru, A; Gunthakandla, S; Sailaja B; Ayyadevara, R; Venkata R.

    Indian J Psychol Med

    Obsessive-compulsive disorder (OCD) is a chronic debilitating mental illness with waxing and waning courses. The H7 coil used for deep repetitive transcranial magnetic stimulation (dTMS) is designed to produce deeper and broader neuronal stimulation in the dorsomedial prefrontal cortex and anterior cingulate…

    OCD
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  4. The Clinical Efficacy of Accelerated Deep Repetitive Transcranial Magnetic Stimulation in Depression and Obsessive-Compulsive Disorder: Multi-centric Real-World Observational Data

    Aswin K. Mudunuru, M S. Reddy, Kartik Valipay, Balaji S. A, Madhiha M, Chandresh N, Chandrasekhar K, Prasad R. Gundugurti

    Cureus  ·  2024

    Of late, the interest in accelerated treatment protocols in repetitive transcranial magnetic stimulation (TMS) for the treatment of depression and obsessive-compulsive disorder (OCD) has been gaining momentum. Studies have already found that the patterned theta burst stimulation is non-inferior to the standard…

    OCD
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  5. Treatment strategies for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A network meta-analysis of randomised controlled trials

    Satish Suhasa, Palash Kumar Malob, Vijay Kumara, Thomas Gregor Issaca, Nellai K. Chithraa, Binukumar Bhaskarapillaib, Y. C. Janardhan Reddyaand Naren P. Rao

    THE WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY2023, VOL. 24, NO. 2, 162–177

    In the last couple of decades, newer treatment modalities, including neuromodulation through brain stimulation and psychosurgery have been examined to treat SRI-resistant OCD. A systematic review of brain stimulation treatments for resistant OCD suggested the efficacy of low-frequency TMS over the supplementary…

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  6. Real-world data of non-invasive stimulation of the human insula-prefrontal cortices using deep TMS to treat anxiety for occupational stress and generalized anxiety disorder

    Rodrigo Moraga-Amaro, Paula Muñoz, Tomás Villalobos, Sergio Linsambarth, Francisco Maldonado, Valeria Meirone, Bruno Femopase, Jimmy Stehberg

    Psychiatry Research  ·  2023

    Anxiety disorders, including occupational stress and generalized anxiety disorder (GAD), are prevalent mental health conditions with significant impacts on individuals' daily functioning and quality of life. Deep Transcranial Magnetic Stimulation (TMS) is a non-invasive brain stimulation technique that holds promise in alleviating…

    AnxietyOCD
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  7. Depressive symptoms during deep transcranial magnetic stimulation or sham treatment for obsessive-compulsive disorder

    Orri Smárason,  Peter J. Boedeker,  Andrew G. Guzick,  Aron Tendler,  Sameer A. Sheth,  Wayne K. Goodman,  Eric A. Storch

    Journal of Affective Disorders  ·  2024

    Evidence suggests that depressive symptoms tend to improve concurrently with obsessive-compulsive disorder (OCD) symptoms during cognitive behavioral therapy (CBT), despite depression not being the primary target of intervention. Studies examining the temporal or mediational relationships of OCD and depressive symptoms have indicated…

    DepressionOCD
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  8. Accelerated deep transcranial magnetic stimulation using iTBS protocol for refractory obsessive-compulsive disorder

    Sachin Reddy, Shyam Sundar, Arumugham Vasundhra, Teotia Pavan, Kumar Pyda

    Brain Stimulation  ·  2023

    Two patient cases illustrate the safety and potential clinical effectiveness of an accelerated deep transcranial magnetic stimulation (dTMS) protocol as an adjunctive approach in treating OCD. In contrast to the conventional once-daily protocol, the accelerated protocol may lead to quicker clinical improvement.…

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  9. Safety and efficacy of H7 deep transcranial magnetic stimulation in adolescent obsessive‐compulsive disorder: A case report

    Ruchira Das, Pooja Sharma, Ambika Sundas, Nishant Goyal, Gulesh Kumar, Devangi Shukla, Chandramouli Roy, Basudeb Das

    Asian Journal of Psychiatry  ·  2023

    We describe the first instance of dTMS application using H7 coil in an adolescent for childhood-onset OCD to evaluate the safety and efficacy of dTMS as an add-on treatment leading to the rapid and significant clinical improvement shown after 10 sessions in…

    OCD
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  10. Brain activation alterations with adjunctive deep transcranial magnetic stimulation in obsessive-compulsive disorder: an fMRI study

    Sachin Reddy, Umesh Shreekantiah, Nishant Goyal and Chandramouli Roy

    CNS Spectrums  ·  2023

    Obsessive-compulsive disorder (OCD) stands as one of the most prevalent neuropsychiatric disorders, surpassing the lifetime prevalence of schizophrenia and bipolar disorders. Many individuals with OCD do not adequately respond to currently available pharmacological and psychotherapeutic interventions. Consequently, there is growing interest in…

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  11. Depressive symptoms during deep transcranial magnetic stimulation or sham treatment for obsessive-compulsive disorder

    Orri Smárason, Peter J. Boedeker, Andrew G. Guzick, Aron Tendler, Sameer A. Sheth, Wayne K. Goodman, Eric A. Storch

    Journal of Affective Disorders  ·  2024

    Existing evidence suggests a concurrent improvement in depressive symptoms alongside obsessive-compulsive disorder (OCD) symptoms during cognitive behavioral therapy (CBT), even though depression is not the primary focus of the intervention. Studies exploring the temporal and mediational links between OCD and depressive symptoms…

    DepressionOCD
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  12. Treatment strategies for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A network meta-analysis of randomised controlled trials

    Satish Suhas, Palash Kumar Malo, Vijay Kumar, Thomas Gregor Issac, Nellai K. Chithra, Binukumar Bhaskarapillai, Y. C. Janardhan Reddy &Naren P. Rao

    The World Journal of Biological Psychiatry  ·  2023

    Treatment-resistant obsessive-compulsive disorder (OCD)  is a chronic debilitating illness. Numerous interventions have been studied, to varying success, in published randomized controlled trials. Objective: Conduct a network meta-analysis (NMA) to compare the efficacy of all interventions in SRI-resistant OCD from published Randomised controlled…

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  13. Transcranial Magnetic Stimulation in Obsessive-Compulsive Disorder

    Tal Harmelech PhD, Yiftach Roth PhD, Aron Tendler MD

    Psychiatric Clinics of North America  ·  2023

    Key Points: Converging lines of evidence suggest that OCD involves dysfunction of limbic cortico-striato-thalamo-cortico loops including the orbitofrontal cortex, medial prefrontal cortex (mPFC) and anterior cingulate cortex (ACC). The H7 Coil was FDA-cleared for treatment-refractory OCD based on results of two RCTs.…

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  14. Cost-effectiveness analysis of deep transcranial magnetic stimulation relative to evidence-based strategies for treatment-refractory obsessive-compulsive disorder

    Sean T. Gregory, Wayne K. Goodman, Brian Kay, Bradley Riemann, Eric A. Storch

    Journal of Psychiatric Research  ·  2022

    OCD affects ~1.2% of individuals each year and confers significant impairment. Approximately 40–60% of adults respond to SRIs; CBT response rates range from 70 to 85%. However, partial- and non-response is common, resulting in a sizable number of treatment refractory individuals Deep TMS provides an additional…

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  15. Long-term outcomes of a course of deep TMS for treatment-resistant OCD

    T Harmelech, A Tendler, MK Arikan, HL çetin, MT Esmeray, R Ilhan, R Vidrine, O Muir, et al.

    Brain Stimulation  ·  2022

    The Deep TMS H7 Coil for treatment-resistant OCD has demonstrated 38% response rate that was sustained for at least a month in a multicenter randomized controlled trial. In real-world clinical practice settings 52.4% of patients achieved at least one month sustained response.…

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  16. Electrical field measurements and simulations of the H7 and D-B80 coils: Non-equivalence of the TMS coils for obsessive compulsive disorder

    Tzirini M, et al

    Brain Stimulation  ·  2021

    In 2018, the FDA cleared deep transcranial magnetic stimulation (BrainsWay Deep TMS) with the H7 coil for obsessive-compulsive disorder (OCD) treatment following a double-blinded placebo-controlled multicenter trial. Magventure's D-B80 Coil was FDA-cleared in August 2020 to treat Obsessive-Compulsive Disorder (OCD), using the…

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  17. Deep repetitive TMS with the H7 coil is sufficient to treat comorbid MDD and OCD

    A. Tendler, Y. Roth, T. Harmelech

    Brain Stimulation  ·  2021

    OCD patients frequently have additional psychiatric illness, the most common being MDD. In 2018 the FDA cleared Deep TMS H7 Coil for the treatment of refractory OCD, based on the efficacy results of a multicenter study. The H7 Coil and its stimulation…

    DepressionOCD
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  18. What is Anxiety? Overview, Statistics and Treatment Options

    Anxiety is a key aspect of many mental health disorders and a central theme in the world of mental health. Read on to learn more about this common concern.

    OCD
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