Mental Health / Psychiatry
Peer-reviewed studies and reviews on Deep TMS for Depression.
Showing Depression · 1–18 of 96
Suicide is the 10th leading cause of death in US adults. Standard once-daily repetitive transcranial magnetic stimulation (rTMS) can reduce suicidal ideation. Yet, antidepressant and anti-suicidal effects often take several weeks to emerge, while rapid improvement is often required. Accelerated TMS has…
Late stages of Lyme disease include cognitive impairment, such as memory loss, slowed handling of information and substandard abstract reasoning. High frequency deep transcranial magnetic stimulation (dTMS) over the left prefrontal cortex (lPFC) has been shown to improve cognitive functioning for patients…
Major Depressive Disorder (MDD) and Alzheimer's disease (AD) represent two of the most prevalent diseases worldwide. Notably, it is estimated that 30%-50% of individuals with AD have co-occurring MDD and there are overlapping symptoms across numerous domains. Methods: In this pilot study,…
The optimal dose (number of pulses per session) of repetitive transcranial magnetic stimulation (rTMS), using the H-coil, in major depressive disorder (MDD) has not previously been reported. Objective: To explore the relationship between rTMS dose and antidepressant effect, and collect data for…
Brainsway dTMS is FDA approved for TRD. Multiple studies prove the efficacy of Ketamine in TRD. There are case reports discussing the combination between Ketamine and rTMS in TRD Objective: To assess the clinical impact of Brainsway dTMS and Brainsway dTMS combined…
Major depressive disorder (MDD) is a leading cause of global disability and is notably prevalent in older adults. Deep transcranial magnetic stimulation (dTMS), specifically the H1-coil targeting the lateral prefrontal cortex, is approved for adults with treatment-resistant MDD and has shown promise…
Recruitment challenges are inherent in clinical research, and are particularly pronounced in older adults with depression, who often face unique barriers such as medical comorbidities and infrequent help-seeking behaviour. Neurostimulation techniques, like deep transcranial magnetic stimulation (dTMS), are often unfamiliar to patients…
Late-life depression (LLD) is a prevalent and often underdiagnosed condition in older adults, associated with significant cognitive, functional, and medical burdens. Conventional treatments frequently present limitations in this population, underscoring the need for safer, more effective alternatives. Objective: This review evaluates the…
Transcranial magnetic stimulation (TMS) uses magnetic pulses to induce electrical current in the underlying neuronal tissue. A variety of TMS coils exist on the market, differing primarily in configuration, orientation, and flexibility of the wire windings of the coil. Deep TMSTM utilizes…
Transcranial magnetic stimulation (TMS) is increasingly used off-label for posttraumatic stress disorder (PTSD), often applying protocols developed for depression. While prior studies suggest high-frequency TMS can improve PTSD symptoms, few have been adequately powered to compare protocols. We examined whether three common TMS protocols yield…
Data suggests that the available therapeutic tools are still insufficient to deal with suicidality. Non-Invasive Brain Stimulation techniques (NIBS) have entered the recognized guidelines for therapies in psychiatry due to the advantages related to safety and tolerability. Objective: The purpose of this…
Suicidality is a leading cause of death in major depressive disorder (MDD), yet actively suicidal patients are rarely included in neuromodulation trials. Evidence for deep transcranial magnetic stimulation (dTMS) in this group is limited. Objective: To assess the safety and efficacy of…
Promising clinical benefits were observed with d-cycloserine (DCS) augmentation of intermittent theta-burst stimulation (iTBS), presumably by enhancing long-term potentiation (LTP) through NMDA receptor agonism (Cole et al., 2022). However, the applicability of this trial and accessibility of this approach are unknown. Ojective: N/A Methods: N/A Results: We…
One third of the depressed patients are not improved by antidepressant drugs and psychological treatments, and there is a need for additional treatments. Repetitive transcranial magnetic stimulation (rTMS) is being developed towards an alternative in treatment-resistant depression. Deep transcranial stimulation (dTMS) with the Hesel-coil…
Aerobic exercise (AEx) is effective in reducing depressive symptoms whether employed singularly or with other anti-depressant treatments. The safety and efficacy of repetitive transcranial magnetic stimulation (rTMS) for treatment of depression is also well documented. Given the benefits of both AEx and rTMS individually, it seems plausible that…
MDD is the most common comorbidity with OCD; more than 50% of OCD patients meet lifetime criteria for MDD or dysthymia. Depression can significantly worsen OCD treatment outcomes and elevate the risk for suicide. While the multi-center-tested and FDA indicated Deep TMS treatment for OCD uses the H7 Coil to target dorsomedial prefrontal cortex…
The DSM-5 classifies MDD as a depressed mood or a loss of interest or pleasure in daily activities for more than two consecutive weeks. Due to the nature of symptoms associated with major depression, many studies have looked at the correlation between…
Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive technique with few side effects that has been reported to be effective in the treatment of major depressive disorder (MDD). At present, no randomized controlled trials (RCT) have compared the efficacy and safety of rTMS delivered by the…
