Showing Clinical Research · 1–18 of 303
Functional, molecular and genetic neuroimaging has highlighted the existence of brain anomalies and neural vulnerability factors related to obesity and eating disorders such as binge eating or anorexia nervosa. In particular, decreased basal metabolism in the prefrontal cortex and striatum as well…
Although repetitive transcranial magnetic stimulation (rTMS), electroconvulsive therapy (ECT), ketamine, and esketamine have established antidepressant effects, their effects on suicide outcomes are less reported. Objective: This comprehensive narrative review aims to analyze the antisuicidal effects of these interventions in individuals with major…
Deep-brain transcranial magnetic stimulation (dTMS) could provide new, non-invasive therapeutic options for various psychiatric and neurological disorders. Objective: Figures of merit (FoMs) are proposed to evaluate and compare dTMS coil designs. These FoMs characterize the depth of electric field penetration, scalp stimulation,…
Deep transcranial magnetic stimulation (dTMS) utilizes different H-coils to study and treat a variety of psychiatric and neurological conditions with identifiable brain targets. The availability of this technology is dramatically changing the practice of psychiatry and neurology as it provides a safe…
In a pilot study involving methamphetamine dependents receiving deep Transcranial Magnetic Stimulation (dTMS) targeting the medial prefrontal and cingulate cortices with H7 coil (Brainsway, Israel), we assessed clinical outcomes from patients receiving 20 sessions of dTMS treatments over 4 weeks (5 days…
Stimulation of deeper brain structures by transcranial magnetic stimulation (TMS) may be beneficial in the treatment of several neurological and psychiatric disorders. Objective: This paper presents numerical simulation of deep transcranial magnetic stimulation (dTMS) by considering double cone, H-and Halo coils. Methods:…
The efficacy of deep repetitive transcranial magnetic stimulation (dTMS) for obsessive compulsive disorder (OCD) was recently confirmed in a Food and Drug Administration-regulated, multicenter, sham-controlled study. In this study, patients who failed pharmacotherapy underwent individually tailored provocations just prior to each stimulation session,…
Deep transcranial magnetic stimulation (dTMS) is effective in treatment of Major Depressive Disorder (MDD), and in re-treatment in case of relapse. Objective: Our study evaluates the long-term durability of dTMS in MDD. Methods: Seventeen patients that responded to dTMS treatment evaluated. Follow-up…
Several different H-coils have been evaluated for the treatment of a variety of psychiatric and neurological disorders, including major depression, addiction, and blepharospasm, with encouraging results. This has prompted the development of novel H-coils designed to target specific brain regions, and diseases,…
Suicide is the 10th leading cause of death in US adults. Standard once-daily repetitive transcranial magnetic stimulation (rTMS) can reduce suicidal ideation. Yet, antidepressant and anti-suicidal effects often take several weeks to emerge, while rapid improvement is often required. Accelerated TMS has…
Because several targets of s-TMS studies play an important role in cognitive performance, the excitation or inhibition of these cortical areas could impair the patient’s performance in certain cognitive domains. Long-term studies assessing the effects of TMS on cognition have, in fact, shown…
Cannabis use disorder (CUD) is a significant public health problem and no medical treatments have received regulatory approval to date. Deep repetitive transcranial magnetic stimulation (dTMS) provides brief powerful bursts of electromagnetic stimulation to brain networks implicated in psychiatric disorders and the…
rTMS can decrease cravings for drugs in a cue dependent fashion. dTMS is efficacious in smoking cessation with sustained quitting when combined with exposure therapy. However, no studies have utilized real world exposure to increase cravings prior to treatment with cocaine use…
Cocaine dependence is a substantial public health problem. Objective: The aim of this study is to evaluate the effect of high frequency deep transcranial magnetic stimulation (dTMS) on craving in patients with cocaine use disorder (CUD). Methods: Seven men with CUD and…
The H-coils are a new development in transcranial magnetic stimulation (TMS) research, allowing direct stimulation of deeper neuronal pathways than does standard TMS. Objective: This study assessed possible health risks, and some cognitive and emotional effects, of two H-coil versions designed to…
Late stages of Lyme disease include cognitive impairment, such as memory loss, slowed handling of information and substandard abstract reasoning. High frequency deep transcranial magnetic stimulation (dTMS) over the left prefrontal cortex (lPFC) has been shown to improve cognitive functioning for patients…
Brain network dysfunction, particularly within the default mode network (DMN), is an increasingly apparent contributor to the clinical progression of Alzheimer's disease (AD). Repetitive transcranial magnetic stimulation (rTMS) can target key DMN hubs, maintain signaling function, and delay or improve clinical outcomes…
Focal rTMS has been applied to improve cognition in Alzheimer's disease (AD) with conflicting results. H Coils are suitable for targeting wider neuronal structures compared with traditional Figure-8 coils. In particular, the H2 Coil stimulates simultaneously the frontal-parietal-temporal lobes bilaterally. Objective: Evaluate…
