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Mental Health / Psychiatry

Addiction

Peer-reviewed studies and reviews on Deep TMS for Addiction.

Showing Addiction  ·  19–36 of 39

  1. Deep rTMS of the insula and prefrontal cortex in smokers with schizophrenia: Proof-of-concept study

    Moeller SJ, Gil R, Weinstein JJ, Baumvoll T, Wengler K, Fallon N, Van Snellenberg JX, Abeykoon S, et al.

    Schizophrenia (Heidelb

    Patients with schizophrenia have a high prevalence of cigarette smoking and respond poorly to conventional treatments, highlighting the need for new therapies. Objective: This was a mechanistic, proof-of-concept study using bilateral deep repetitive transcranial magnetic stimulation (dTMS) of insular and prefrontal cortices…

    AddictionSchizophrenia
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  2. Deep magnetic stimulation targeting the medial prefrontal and anterior cingulate cortices for methamphetamine use disorder: a randomised, double-blind, sham-controlled study

    Di Zhao, Ningning Zeng, Hang-Bin Zhang, Yi Zhang, Jiatong Shan, Huichun Luo, Abraham Zangen, and Ti-Fei Yuan

    General Psychiatry  ·  2023

    Prior research has underscored the importance of cravings in substance use disorders (SUDs) and the potential of repetitive transcranial magnetic stimulation (rTMS) in mitigating these cravings. Crucial brain regions, including the medial prefrontal cortex (MPFC) and anterior cingulate cortex (ACC), are implicated…

    Addiction
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  3. Efficacy of insula deep repetitive transcranial magnetic stimulation combined with varenicline for smoking cessation: A randomized, double-blind, sham controlled trial

    Christine Ibrahim, Victor M. Tang, Daniel M. Blumberger, Saima Malik, Rachel F. Tyndale, Alisson P. Trevizol, Mera S. Barr, Zafiris J. Daskalakis, et al.

    Brain Stimulation  ·  2023

    Current treatments for smoking cessation face limitations in terms of efficacy, particularly in achieving sustained abstinence. A substantial body of evidence points to the involvement of the insula in nicotine addiction. Objective: This study aimed to assess the effectiveness of bilateral repetitive…

    Addiction
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  4. Moderators of the Response to Deep TMS for Smoking Addiction

    Roman Gersner, Noam Barnea-Ygael, Aron Tendler

    Frontiers in Psychiatry  ·  2023

    Recently, the FDA granted clearance for deep repetitive transcranial magnetic stimulation (Deep TMS™) as a short-term smoking cessation treatment. However, there remains uncertainty regarding the characteristics of participants who are more likely to benefit from this treatment. Objective & Methods: This study…

    Addiction
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  5. Transcranial Magnetic Stimulation as a Tool to Promote Smoking Cessation and Decrease Drug and Alcohol Use

    Harmelech, T.; Hanlon, C.A.; Tendler, A

    Brain Sciences  ·  2023

    Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive, drug-free, neural-circuit-based therapeutic tool that was recently cleared by the United States Food and Drug Associate for the treatment of smoking cessation. TMS has been investigated as a tool to reduce consumption and craving…

    Addiction
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  6. Repetitive transcranial magnetic stimulation in alcohol dependence: A randomized, double-blind, sham-controlled proof-of-concept trial targeting medial prefrontal and anterior cingulate cortex

    M Harel, I Perini, R Kämpe, U Alyagon, H Shalev, I Besser, R Kampe, WH Sommer, et al.

    Biological Psychiatry  ·  2022

    Alcohol addiction is associated with a high disease burden, and treatment options are limited. Objective: In a proof-of-concept study, the authors used Deep TMS to target circuitry associated with the pathophysiology of alcohol addiction and evaluated clinical outcomes and associated neural signatures…

    Addiction
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  7. Repetitive Transcranial Magnetic Stimulation for Smoking Cessation: a Pivotal Multicenter Double-Blind Randomized Controlled Trial

    A Zangen, H Moshe, D Martinez, N Barnea-Ygael, T Vapnik, A Bystritsky, W Duffy, D Toder, et al.

    World Psychiatry  ·  2021

    Deep TMS is a non-invasive brain stimulation method increasingly used to treat psychiatric disorders, primarily depression. Initial studies suggest that Deep TMS may help to treat addictions, but evaluation in multicenter randomized controlled trials (RCTs) is needed. Objective: This multicenter double-blind RCT intended to evaluate…

    Addiction
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  8. Deep Transcranial Magnetic Stimulation Over the Medial Prefrontal and Anterior Cingulate Cortex Alters Brain Connectivity and Reduces Relapses to Alcohol Use

    M Harel, N Barnea-Ygael, H Shalev, I Besser, M Salti, R Kampe, M Heilig, A Zangen

    Biological Psychiatry  ·  2019

    Alcohol use disorder (AUD) is a highly prevalent disorder with limited treatment options, partially due to limited understanding of its basic neuropathology. Nevertheless, abnormal neuronal activity in the medial prefrontal and anterior cingulate cortices (mPFC and ACC, respectively) have been suggested to…

    Addiction
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  9. Can deep transcranial magnetic stimulation (DeepTMS) be used to treat substance use disorders (SUD)? A systematic review

    K.K Kedzior, I. Gerkensmeier, M. Schuchinsky

    BMC Psychiatry  ·  2018

    Deep transcranial magnetic stimulation (Deep TMS™) is a non-invasive method of stimulating widespread cortical areas and, presumably, deeper neural networks. Objective: The current study assessed the effects of Deep TMS in the treatment of substance use disorders (SUD) using a systematic review.…

    Addiction
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  10. Effects of Deep Transcranial Magnetic Stimulation (Deep TMS) on Anti-inflammatory Gut Bacterial Species in Obesity

    A Ferrulli, M Toscano, M Adamo, I Terruzzi, L Drago, L Luzi

    Diabetes  ·  2018

    Growing evidence highlights the crucial role of gut microbiota in affecting different aspects of obesity. Potential mechanisms for microbial control over eating behavior include microbiota influence on reward and satiety pathways, neurotransmitters release, and hypothalamic-pituitary-adrenal (HPA) axis modulation. Deep TMS™ is amethodology…

    Addiction
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  11. Deep Transcranial Magnetic Stimulation Attenuates Depressive and Anxiety Symptoms Associated with Obesity

    A Ferrulli, C Marcì, V Dangelo, L Luzi

    Diabetes  ·  2019

    The association between obesity and psychological distress has been widely demonstrated. Systematic reviews have highlighted the bidirectional nature of this relationship. Strategies aimed at improving dopamine function may be beneficial in the treatment of both obesity and the associated psychological symptoms. Deep…

    Addiction
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  12. Deep Transcranial Magnetic Stimulation Acutely ModulatesNeuro-EndocrinePathwaysUnderlyingObesity

    A Ferrulli, M Adamo, S Massarini, L Luzi

    Endocrine Abstracts  ·  2018

    Deep Transcranical Magnetic Stimulation (Deep TMS™) is a non-invasive modulation technique that has been shown to affect the mesolimbic and mesostriatal dopaminergic pathways. Consistent with this, Deep TMS is widely used as a therapeutic tool in neuro-psychiatric disorders associated with abnormal cortical…

    Addiction
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  13. High Frequency Deep TMS over the Bilateral Insula is Associated with Increased Degree Centrality in the Prefrontal Cortex of Obese Subjects: Preliminary Evidence

    F Devoto, A Ferrulli, L Zapparoli, S Massarini, C Verga, G Banfi, E Paulesu, L Luzi

    Brain Stimulation  ·  2019

    Obese subjects can be considered “food addicted”. Since there is growing evidence for the role of deep Transcranial Magnetic Stimulation (Deep TMS™) in reducing craving for different addictions, the authors proposed high frequency (HF) Deep TMS as a mean to reduce food…

    Addiction
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  14. Transcranial magnetic stimulation for the treatment of cocaine addiction: evidence to date

    C Bolloni, P Badas, G Corona, M Diana

    Substance Abuse and Rehabilitation  ·  2018

    There is a common consensus in considering substance-use disorders (SUDs) a devastating chronic illness with social and psychological impact. Despite significant progress in understanding the neurobiology of SUDs, therapeutic advances have proceeded at a slower pace, in particular for cocaine-use disorder (CUD).…

    Addiction
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  15. Transcranial Magnetic Stimulation (TMS) in the Elderly

    I.G Iriarte, M George

    Current Psychiatry Reports  ·  2018

    Repeated daily prefrontal Transcranial Magnetic Stimulation (rTMS) for 4–6 weeks for treating depression was first proposed as a treatment in 1994, and was FDA approved 14 years later in 2008. Almost a decade later, the field is still rapidly developing and changing.…

    Addiction
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  16. A Review of Brain Stimulation Methods to Treat Substance Use Disorders

    A.S Coles, K Kozak, T.P George

    The American Journal on Addictions  ·  2018

    Substance use disorders (SUDs) are a leading cause of disability worldwide. While several pharmacological and behavioral treatments for SUDs are available, these may not be effective for all patients. Recent studies using non-invasive neuromodulation techniques including repetitive transcranial magnetic stimulation(rTMS), transcranial direct…

    Addiction
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  17. Effects of repetitive transcranial magnetic stimulation (rTMS) on craving and substance consumption in patients with substance dependence: A systematic review and meta-analysis

    J.J.Q Zhang, K.N.K Fong, R.G Ouyang, A.M.H Siu, G.S Kranz

    Addiction  ·  2019

    rTMS is increasingly used as an intervention for treating substance dependence. Objective: The authorsaimed to assess evidence of the anti-craving and consumption-reducing effects of rTMS in patients with alcohol, nicotine, and illicit drug dependence. Methods: A systematic review and meta-analysis of 26…

    Addiction
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  18. How Deep is the Deep Transcranial Magnetic Stimulation (Deep TMS)?

    K.K Kedzior, I Gerkensmeier, M Schuchinsky

    Brain Stimulation  ·  2017

    Deep transcranial magnetic stimulation (Deep TMS™) is a non-invasive method of stimulating widespread cortical areas and presumably deeper neural networks. Objective: The current study assessed the efficacy of Deep TMS in the treatment of substance use disorders (SUD) using a systematic review…

    Addiction
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