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Basic Science Studies

Peer-reviewed studies and reviews on Deep TMS for Basic Science Studies.

Showing Basic Science Studies  ·  19–29 of 29

  1. Comparison of superficial TMS and deep TMS for major depression

    A Ginou, Y Roth, A Zangen

    Brain Stimulation  ·  2014

    Publication & Date:Brain Stimulation 7:19 (2014) Investigators:A Ginou, Y Roth, A Zangen

  2. Transcranial magnetic stimulation of deep brain regions: evidence for efficacy of the H-Coil

    A Zangen, Y Roth, B Voller, M Hallett

    Journal of Clinical Neurophysiology  ·  2005

    Standard coils used in research and the clinic for noninvasive magnetic stimulation of the human brain are not capable of stimulating deep brain regions directly. As the fields induced by these coils decrease rapidly as a function of depth, only very high…

  3. A Coil Design for Transcranial Magnetic Stimulation of Deep Brain Regions

    Y Roth, A Zangen, M Hallett

    Journal of Clinical Neurophysiology  ·  2002

    Noninvasive magnetic stimulation of the human central nervous system has been used in research and the clinic for several years. However, the coils used thus far stimulate mainly the cortical brain regions and could not stimulate deeper brain regions directly. Objective: The…

  4. Three-Dimensional Distribution of the Electric Field Induced in the Brain by Transcranial Magnetic Stimulation Using Figure-8 and Deep H-Coils

    Y Roth, A Amir, Y Levkovitz, A Zangen

    Journal of Clinical Neurophysiology  ·  2007

    The H-coils are a novel development in transcranial magnetic stimulation (TMS), designed to achieve effective stimulation of deep neuronal regions without inducing unbearable fields cortically, thus broadly expanding the potential feasibility of TMS for research and for treating various neurologic disorders. Objective:…

  5. Transcranial magnetic stimulation induces increases in extracellular levels of dopamine and glutamate in the nucleus accumbens

    A Zangen, K Hyodo

    Neuroreport  ·  2002

    Transcranial magnetic stimulation (TMS) is a non-invasive approach used for stimulating the human brain.Repetitive stimulation over the prefrontal cortex has proven effective in the treatment of major depression, however the mechanism of the antidepressant action is unknown. Objective: Since the nucleus accumbens…

  6. Site-Specific Antidepressant Effects of Repeated Subconvulsive Electrical Stimulation: Potential Role of Brain-Derived Neurotrophic Factor

    R Gersner, E Toth, M Isserles, A Zangen

    Biological Psychiatry  ·  2010

    Electroconvulsive therapy (ECT) is a very effective treatment for major depression. This method involves robust non focal stimulation of the brain and can normalize both neurochemical alterations and depressive behavior in animal models. The authors hypothesized that short stimulation sessions of specific…

  7. Inherited behaviors, BDNF expression and response to treatment in a novel multi factorial rat model for depression

    R Gersner, R Gal, O levit, H Moshe, A Zangen

    International Journal of Neuropsychopharmacology  ·  2014

    Major depressive disorder (MDD) is a common and devastating mental illness behaviorally characterized by various symptoms, including reduced motivation, anhedonia and psychomotor retardation. Although the etiology of MDD is still obscure, a genetic predisposition appears to play an important role. Objective: This…

  8. Prelimbic Stimulation Ameliorates Depressive-Like Behaviors and Increases Regional BDNF Expression in a Novel Drug-Resistant Animal Model of Depression

    H Moshe, R Gal, N Barnea-Ygael, T Gulevsky, U Alyagon, A Zangen

    Brain Stimulation  ·  2016

    Approximately one third of all major depression patients fail to respond to conventional pharmacological antidepressants, and brain stimulation methods pose a promising alternative for this population. Recently, based on repeated multifactorial selective inbreeding of rats for depressive-like behaviors, we introduced a novel…

  9. The Role of Medial Prefrontal Cortex in Theory of Mind: A Deep rTMS Study

    L Krause, P.G Enticott, A Zangen, P.B Fitzgerlad

    Behavioral Brain Research  ·  2012

    Neuroimaging studies suggest that the medial prefrontal cortex (mPFC) plays a central role in cognitive theory of mind (ToM). Objective: To assess more definitively, using deep transcranial magnetic stimulation (Deep TMS™), whether the mPFC plays a central role in ToM. Method: Sixteen…

  10. Deep Transcranial Magnetic Stimulation for the Treatment of Addiction: Electric Field Distribution Modeling

    S Fiocchi, E Chiaramello, L Luzi, A Ferrulli, M Bonato, Y Roth, A Zangen, P Ravazzani

    Journal of Electromagnetics, RF, and Microwaves in Medicine and Biology  ·  2018

    Deep Transcranial Magnetic Stimulation (Deep TMS™) is a neurostimulation technique for deep brain structures that has recently been successfully applied in the clinic for treatment of addiction. In contrast to conventional magnetic stimulation, which uses planar coils (figure 8) to target specific…

  11. Interhemispheric Cortico-cortical Paired Associative Stimulation of the Prefrontal Cortex Jointly Modulates Frontal Asymmetry and Emotional Reactivity

    S Zibman, E Daniel, U Alyagon, A Etkin, A Zangen

    Brain Stimulation  ·  2018

    As advances in neuroimaging further our understanding of the brain's functional connectivity, neuropsychology has moved away from a regional approach of attributing behavior to a specific region towards a network approach, attributing behavior to interconnected regions. A prime example of this is…