This multicenter study examined Brainsway® Deep TMS (Transcranial Magnetic Stimulation) as a treatment for major depressive disorder. The study included over 200 patients who were randomly assigned for real or sham Deep TMS (20 sessions) over a period of a month. Thereafter, patients underwent a maintenance period that included additional two sessions/week over three months. The study found that the real Deep Transcranial Magnetic Stimulation treatment was superior to the sham treatment and induced a beneficial effect that was evident after both the acute phase and the maintenance phase. The results indicate that Brainsway Deep TMS is effective and safe as a treatment for major depressive disorder.