A study, “Deep transcranial magnetic stimulation alters resting-state neurophysiological traits in major depressive disorder”, authored by Nathaniel A. Shanok, Santiago Rodriguez, Sabrina Muzac, Carla Huertas Del Pino, Leah Brown, and Raul Rodriguez, evaluated the effects of a standard course of Deep TMS treatments on brain activation patterns during rest.
Before the first Deep TMS session and after the last Deep TMS session, participants completed a PHQ-9 assessment to verify the intensity of depressive symptoms and underwent quantitative electroencephalography (QEEG) recording. The QEEG recordings showed reduced slow-frequency brain activity (delta and theta waves) in the prefrontal cortex after treatments. Baseline QEEG activity in the frontal lobe predicted whether a participant would be a responder or non-responder to the treatment with 93 percent accuracy
