Major depressive disorder (‘MDD’ or depression) is the leading cause of disability globally, affecting nearly 350 million people worldwide. It is well known that MDD substantially impacts quality of life. Yet, much less is known about how treatments for depression impact quality of life.
Most depression assessments focus on symptom reduction, with clinicians commonly using scales like the Hamilton Depression Rating Scale to evaluate outcomes. These scales measure the deficits from depression, including suicidality, difficulties with sleep, work, sadness, worry, physical complaints, appetite etc. However, the resolution of those deficits does not necessarily translate into a positive quality of life.
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