This multicenter study examined Brainsway® Deep TMS (Transcranial Magnetic Stimulation) as a treatment for major depressive disorder. The study included over 200 patients who were randomly assigned for real or sham Deep TMS (20 sessions) over a period of a month. Thereafter, patients underwent a maintenance period that included additional two sessions/week over three months. The study found that the real Deep Transcranial Magnetic Stimulation treatment was superior to the sham treatment and induced a beneficial effect that was evident after both the acute phase and the maintenance phase.
The multicenter double blinded randomized controlled trial results show Brainsway Deep TMS to be efficacious and safe for drug-resistant depression, with a stable effect over 3 months of maintenance treatment. A clinically significant improvement was seen even in highly treatment-resistant patients who did not respond to three or more antidepressant medications in the current episode